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Pharmacogenetics of tacrolimus: ready for clinical translation?
Tacrolimus (Tac) exhibits an interindividual pharmacokinetic variability that affects the dose required to reach the target concentration in blood. Tac is metabolized by two enzymes of the cytochrome P450 family, CYP3A5 and CYP3A4. The effect of the CYP3A5 genotype on Tac bioavailability has been de...
שמור ב:
| Main Authors: | , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Nature Publishing Group
2011
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4089617/ https://ncbi.nlm.nih.gov/pubmed/25028625 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/kisup.2011.14 |
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