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T-cell co-stimulatory blockade in kidney transplantation: back to the bench
It is believed that blocking positive T-cell co-stimulatory pathways should lead to long-term graft acceptance. Despite the exciting initial achievements in experimental animal models, targeting co-stimulatory pathways has shown to be much more complex in the clinic. In addition to multiple binding...
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4089598/ https://ncbi.nlm.nih.gov/pubmed/25018899 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/kisup.2011.8 |
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