Resistin-induced stromal cell-derived factor-1 expression through Toll-like receptor 4 and activation of p38 MAPK/ NFκB signaling pathway in gastric cancer cells

BACKGROUND: Stromal cell-derived factor-1 (SDF-1) (CXC chemokine ligand-12)/CXC chemokine receptor 4 (CXCR4) is involved in the carcinogenesis of human gastric cancer, where it stimulates angiogenesis and favors metastasis of tumor cells to distant organs. In addition, resistin is suggested to be an...

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Hauptverfasser: Hsieh, Yung-Yu, Shen, Chien-Heng, Huang, Wen-Shih, Chin, Chih-Chien, Kuo, Yi-Hung, Hsieh, Meng Chiao, Yu, Hong-Ren, Chang, Te-Sheng, Lin, Tseng-Hsi, Chiu, Yung-Wei, Chen, Cheng-Nan, Kuo, Hsing-Chun, Tung, Shui-Yi
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2014
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4089564/
https://ncbi.nlm.nih.gov/pubmed/24929539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1423-0127-21-59
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