Development of (124)I-Immuno-PET Targeting Tumor Vascular TEM1/Endosialin

Tumor endothelial marker 1 (TEM1/endosialin) is a tumor vascular marker highly overexpressed in multiple human cancers with minimal expression in normal adult tissue. In this study, we report the preparation and evaluation of (124)I-MORAb-004, a (124)I-labeled humanized monoclonal antibody targeting...

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Autori principali: Chacko, Ann-Marie, Li, Chunsheng, Nayak, Madhura, Mikitsh, John L., Hu, Jia, Hou, Catherine, Grasso, Luigi, Nicolaides, Nicholas C., Muzykantov, Vladimir R., Divgi, Chaitanya R., Coukos, George
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4089496/
https://ncbi.nlm.nih.gov/pubmed/24525208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.113.121905
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