A carregar...
Structures of the NLRP14 pyrin domain reveal a conformational switch mechanism regulating its molecular interactions
The cytosolic tripartite NLR receptors serve as important signalling platforms in innate immunity. While the C-terminal domains act as sensor and activation modules, the N-terminal death-like domain, e.g. the CARD or pyrin domain, is thought to recruit downstream effector molecules by homotypic inte...
Na minha lista:
| Main Authors: | , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
International Union of Crystallography
2014
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4089490/ https://ncbi.nlm.nih.gov/pubmed/25004977 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1399004714010311 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|