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Exploiting subtle structural differences in heavy-atom derivatives for experimental phasing

Structure determination using the single isomorphous replacement (SIR) or single-wavelength anomalous diffraction (SAD) methods with weak derivatives remains very challenging. In a recent structure determination of glycoprotein E2 from bovine viral diarrhea virus, three isomorphous uranium-derivativ...

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Detalhes bibliográficos
Main Authors: Wang, Jimin, Li, Yue, Modis, Yorgo
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4089484/
https://ncbi.nlm.nih.gov/pubmed/25004964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1399004714008943
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