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Exploiting large non-isomorphous differences for phase determination of a G-segment invertase–DNA complex

Crystals of the G-segment invertase in complex with a 37-base-pair asymmetric DNA duplex substrate had an unusually high solvent content of 88% and diffracted to a maximal resolution of about 5.0 Å. These crystals exhibited a high degree of non-isomorphism and anisotropy, which presented a serious c...

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Detalhes bibliográficos
Main Authors: Ritacco, Christopher J., Steitz, Thomas A., Wang, Jimin
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3949525/
https://ncbi.nlm.nih.gov/pubmed/24598738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1399004713032392
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