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The genetics and immunobiology of IgA nephropathy

IgA nephropathy (IgAN) represents the leading cause of kidney failure among East Asian populations and the most frequent form of primary glomerulonephritis among Europeans. Patients with IgAN develop characteristic IgA1-containing immune complexes that deposit in the glomerular mesangium, producing...

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Autori principali: Kiryluk, Krzysztof, Novak, Jan
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4089454/
https://ncbi.nlm.nih.gov/pubmed/24892706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI74475
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