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Decrease of Murine Cytomegalovirus–Induced Retinitis by Intravenous Delivery of Immediate Early Protein-3–Specific siRNA

PURPOSE. Retinitis induced by both human and murine cytomegaloviruses following immunosuppression is characterized by progressive loss of retinal architecture, due to necrosis of virus-infected cells as well as widespread apoptosis of uninfected bystander cells. Because small inhibitory RNA molecule...

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Autores principales: Marshall, Brendan, Mo, Juan, Covar, Jason, Atherton, Sally S., Zhang, Ming
Formato: Artigo
Lenguaje:Inglês
Publicado: The Association for Research in Vision and Ophthalmology 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4089418/
https://ncbi.nlm.nih.gov/pubmed/24906861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.14-14375
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