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Lack of TNF-α Promotes Caspase-3–Independent Apoptosis during Murine Cytomegalovirus Retinitis

PURPOSE. Both caspase-dependent and caspase-independent apoptosis contribute to retinal damage during murine cytomegalovirus (MCMV) retinitis, and TNF-α is among the inducers of apoptosis. The aim of this study was to determine the contribution of TNF-α by studying virus replication and apoptosis in...

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Detalhes bibliográficos
Main Authors: Zhang, Ming, Covar, Jason, Marshall, Brendan, Dong, Zheng, Atherton, Sally S.
Formato: Artigo
Idioma:Inglês
Publicado em: Association for Research in Vision and Ophthalmology, Inc. 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3101684/
https://ncbi.nlm.nih.gov/pubmed/21310911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.10-6904
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