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Innate DNA sensing is impaired in HIV patients and IFI16 expression correlates with chronic immune activation

The innate immune system has been recognized to play a role in the pathogenesis of HIV infection, both by stimulating protective activities and through a contribution to chronic immune activation, the development of immunodeficiency and progression to AIDS. A role for DNA sensors in HIV recognition...

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Autors principals: Nissen, S K, Højen, J F, Andersen, K L D, Kofod-Olsen, E, Berg, R K, Paludan, S R, Østergaard, L, Jakobsen, M R, Tolstrup, M, Mogensen, T H
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4089180/
https://ncbi.nlm.nih.gov/pubmed/24593816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cei.12317
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