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Role of microRNA-146a in normal and malignant hematopoietic stem cell function
Regulation of hematopoiesis is controlled by microRNAs (miRNAs). In this review, we focus on miR-146a, and its role in regulating normal and malignant hematopoiesis. miR-146a is a negative regulator of immune cell activation by repressing two targets, TRAF6 and IRAK1. Genetic deletion of miR-146a co...
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Frontiers Media S.A.
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4087671/ https://ncbi.nlm.nih.gov/pubmed/25071842 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2014.00219 |
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