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Role of microRNA-146a in normal and malignant hematopoietic stem cell function

Regulation of hematopoiesis is controlled by microRNAs (miRNAs). In this review, we focus on miR-146a, and its role in regulating normal and malignant hematopoiesis. miR-146a is a negative regulator of immune cell activation by repressing two targets, TRAF6 and IRAK1. Genetic deletion of miR-146a co...

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Detalhes bibliográficos
Main Authors: Zhao, Jimmy L., Starczynowski, Daniel T.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4087671/
https://ncbi.nlm.nih.gov/pubmed/25071842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2014.00219
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