Structure of the LdcB LD-Carboxypeptidase Reveals the Molecular Basis of Peptidoglycan Recognition

Peptidoglycan surrounds the bacterial cytoplasmic membrane to protect the cell against osmolysis. The biosynthesis of peptidoglycan, made of glycan strands crosslinked by short peptides, is the target of antibiotics like β-lactams and glycopeptides. Nascent peptidoglycan contains pentapeptides that...

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Main Authors: Hoyland, Christopher N., Aldridge, Christine, Cleverley, Robert M., Duchêne, Marie-Clémence, Minasov, George, Onopriyenko, Olena, Sidiq, Karzan, Stogios, Peter J., Anderson, Wayne F., Daniel, Richard A., Savchenko, Alexei, Vollmer, Waldemar, Lewis, Richard J.
Format: Artigo
Sprog:Inglês
Udgivet: Cell Press 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4087270/
https://ncbi.nlm.nih.gov/pubmed/24909784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2014.04.015
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