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Wnt5a Evokes Cortical Axon Outgrowth and Repulsive Guidance by Tau Mediated Reorganization of Dynamic Microtubules

Wnt5a guides cortical axons in vivo by repulsion and in vitro evokes cortical axon outgrowth and repulsion by calcium signaling pathways. Here we examined the role of microtubule (MT) reorganization and dynamics in mediating effects of Wnt5a. Inhibiting MT dynamics with nocodazole and taxol abolishe...

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Detalhes bibliográficos
Main Authors: Li, Li, Fothergill, Thomas, Hutchins, B Ian, Dent, Erik W, Kali, Katherine
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4087151/
https://ncbi.nlm.nih.gov/pubmed/23818454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dneu.22102
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