The presence of anti-Tat antibodies in HIV-infected individuals is associated with containment of CD4(+) T-cell decay and viral load, and with delay of disease progression: results of a 3-year cohort study

BACKGROUND: Tat is a key HIV-1 virulence factor, which plays pivotal roles in virus gene expression, replication, transmission and disease progression. After release, extracellular Tat accumulates in tissues and exerts effects on both the virus and the immune system, promoting immune activation and...

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Detalhes bibliográficos
Main Authors: Bellino, Stefania, Tripiciano, Antonella, Picconi, Orietta, Francavilla, Vittorio, Longo, Olimpia, Sgadari, Cecilia, Paniccia, Giovanni, Arancio, Angela, Angarano, Gioacchino, Ladisa, Nicoletta, Lazzarin, Adriano, Tambussi, Giuseppe, Nozza, Silvia, Torti, Carlo, Focà, Emanuele, Palamara, Guido, Latini, Alessandra, Sighinolfi, Laura, Mazzotta, Francesco, Di Pietro, Massimo, Di Perri, Giovanni, Bonora, Stefano, Mercurio, Vito S, Mussini, Cristina, Gori, Andrea, Galli, Massimo, Monini, Paolo, Cafaro, Aurelio, Ensoli, Fabrizio, Ensoli, Barbara
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Short Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4087126/
https://ncbi.nlm.nih.gov/pubmed/24961156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-11-49
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