The presence of anti-Tat antibodies in HIV-infected individuals is associated with containment of CD4(+) T-cell decay and viral load, and with delay of disease progression: results of a 3-year cohort study

BACKGROUND: Tat is a key HIV-1 virulence factor, which plays pivotal roles in virus gene expression, replication, transmission and disease progression. After release, extracellular Tat accumulates in tissues and exerts effects on both the virus and the immune system, promoting immune activation and...

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Autors principals: Bellino, Stefania, Tripiciano, Antonella, Picconi, Orietta, Francavilla, Vittorio, Longo, Olimpia, Sgadari, Cecilia, Paniccia, Giovanni, Arancio, Angela, Angarano, Gioacchino, Ladisa, Nicoletta, Lazzarin, Adriano, Tambussi, Giuseppe, Nozza, Silvia, Torti, Carlo, Focà, Emanuele, Palamara, Guido, Latini, Alessandra, Sighinolfi, Laura, Mazzotta, Francesco, Di Pietro, Massimo, Di Perri, Giovanni, Bonora, Stefano, Mercurio, Vito S, Mussini, Cristina, Gori, Andrea, Galli, Massimo, Monini, Paolo, Cafaro, Aurelio, Ensoli, Fabrizio, Ensoli, Barbara
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2014
Matèries:
Short Report
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4087126/
https://ncbi.nlm.nih.gov/pubmed/24961156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-11-49
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