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PTK7-Src signaling at epithelial cell contacts mediates spatial organization of actomyosin and planar cell polarity

Actomyosin contractility plays a key role in tissue morphogenesis. During mammalian development, PTK7 regulates epithelial morphogenesis and planar cell polarity (PCP) through modulation of actomyosin contractility, but the underlying mechanism is unknown. Here we show that PTK7 interacts with the t...

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Detalhes bibliográficos
Main Authors: Andreeva, Anna, Lee, Jianyi, Lohia, Madhura, Wu, Xiaoji, Macara, Ian G., Lu, Xiaowei
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4086913/
https://ncbi.nlm.nih.gov/pubmed/24703874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2014.02.008
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