A Phase I Study of Bevacizumab, Everolimus, and Panitumumab in Advanced Solid Tumors

PURPOSE: Preclinical data suggests concurrent inhibition of VEGF, mTOR and EGFR pathways may augment anti-tumor and anti-angiogenic effects compared to inhibition of each pathway alone. This study evaluated the maximum tolerated dose /recommended phase II dose and safety and tolerability of bevacizu...

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Bibliografische gegevens
Hoofdauteurs: Vlahovic, Gordana, Meadows, Kellen L., Uronis, Hope E., Morse, Michael A., Blobe, Gerard C., Riedel, Richard F., Zafar, S. Yousuf, Alvarez-Secord, Angeles, Gockerman, Jon, Starodub, Alexander N., Ready, Neal E., Anderson, Elizabeth L., Bendell, Johanna C., Hurwitz, Herbert I.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2012
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4086794/
https://ncbi.nlm.nih.gov/pubmed/22638798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-012-1889-8
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