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Comment on: ApoE-directed therapeutics rapidly clear β-amyloid and reverse deficits in AD mouse models

Cramer et al. (Reports, 23 March 2012: 1503-1506) (1) demonstrated that treatment of APP/PS1ΔE9 mice with bexarotene decreased Aβ pathology and ameliorated memory deficits. We confirm the reversal of memory deficits in APP/PS1ΔE9 mice expressing human APOE3 or APOE4 to the levels of their non-transg...

詳細記述

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書誌詳細
主要な著者: Fitz, Nicholas F., Cronican, Andrea A., Lefterov, Iliya, Koldamova, Radosveta
フォーマット: Artigo
言語:Inglês
出版事項: 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4086452/
https://ncbi.nlm.nih.gov/pubmed/23704552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1235809
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