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Comment on: ApoE-directed therapeutics rapidly clear β-amyloid and reverse deficits in AD mouse models
Cramer et al. (Reports, 23 March 2012: 1503-1506) (1) demonstrated that treatment of APP/PS1ΔE9 mice with bexarotene decreased Aβ pathology and ameliorated memory deficits. We confirm the reversal of memory deficits in APP/PS1ΔE9 mice expressing human APOE3 or APOE4 to the levels of their non-transg...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4086452/ https://ncbi.nlm.nih.gov/pubmed/23704552 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1235809 |
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