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Cyclovirobuxinum D suppresses lipopolysaccharide-induced inflammatory responses in murine macrophages in vitro by blocking JAK-STAT signaling pathway

AIM: Cyclovirobuxinum D (CVB-D), an alkaloid isolated from the Chinese medicinal plant Buxus microphylla, has been found to be effective to treat cardiac insufficiency, arrhythmias and coronary heart disease. In the present study, we investigated the effects of CVB-D on the inflammatory responses in...

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Detalhes bibliográficos
Main Authors: Guo, Dan, Li, Jing-rong, Wang, Ying, Lei, Lin-sheng, Yu, Chuan-lin, Chen, Na-na
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4086391/
https://ncbi.nlm.nih.gov/pubmed/24747164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2014.16
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