Tofacitinib Ameliorates Lipopolysaccharide-Induced Acute Kidney Injury by Blocking the JAK-STAT1/STAT3 Signaling Pathway

Septic acute kidney injury (AKI) is the most common AKI syndrome in the intensive care unit (ICU), and it accounts for approximately half of AKI cases. Tofacitinib (TOFA) is a pan-Janus kinase (JAK) inhibitor that exhibits potent anti-inflammatory activity in rheumatoid arthritis. However, no study...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Biomed Res Int
Main Authors: Yun, Yang, Chen, Jingyu, Wang, Xuejiao, Li, Yingzhuo, Hu, Zhifan, Yang, Pingting, Qin, Ling
Format: Artigo
Jezik:Inglês
Izdano: Hindawi 2021
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7822662/
https://ncbi.nlm.nih.gov/pubmed/33511217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2021/8877056
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