Tofacitinib Ameliorates Lipopolysaccharide-Induced Acute Kidney Injury by Blocking the JAK-STAT1/STAT3 Signaling Pathway

Septic acute kidney injury (AKI) is the most common AKI syndrome in the intensive care unit (ICU), and it accounts for approximately half of AKI cases. Tofacitinib (TOFA) is a pan-Janus kinase (JAK) inhibitor that exhibits potent anti-inflammatory activity in rheumatoid arthritis. However, no study...

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Detalhes bibliográficos
Publicado no:Biomed Res Int
Main Authors: Yun, Yang, Chen, Jingyu, Wang, Xuejiao, Li, Yingzhuo, Hu, Zhifan, Yang, Pingting, Qin, Ling
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7822662/
https://ncbi.nlm.nih.gov/pubmed/33511217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2021/8877056
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