Quercetin sensitizes human glioblastoma cells to temozolomide in vitro via inhibition of Hsp27

AIM: Quercetin is an effective Hsp27 inhibitor and has been reported to facilitate tumor cell apoptosis. The aim of this study was to investigate whether quercetin could sensitize human glioblastoma cells to temozolomide (TMZ) in vitro. METHODS: Both U251 and U87 human glioblastoma cells were treate...

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Bibliographische Detailangaben
Hauptverfasser: Sang, Dong-ping, Li, Ru-jun, Lan, Qing
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2014
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4086384/
https://ncbi.nlm.nih.gov/pubmed/24902789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2014.22
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