Subchondral Bone Plate Thickening Precedes Chondrocyte Apoptosis and Cartilage Degradation in Spontaneous Animal Models of Osteoarthritis

Osteoarthritis (OA) is the most common joint disorder characterised by bone remodelling and cartilage degradation and associated with chondrocyte apoptosis. These processes were investigated at 10, 16, 24, and 30 weeks in Dunkin Hartley (DH) and Bristol Strain 2 (BS2) guinea pigs that develop OA spo...

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Main Authors: Zamli, Zaitunnatakhin, Robson Brown, Kate, Tarlton, John F., Adams, Mike A., Torlot, Georgina E., Cartwright, Charlie, Cook, William A., Vassilevskaja, Kristiina, Sharif, Mohammed
Format: Artigo
Jezik:Inglês
Izdano: Hindawi Publishing Corporation 2014
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4086372/
https://ncbi.nlm.nih.gov/pubmed/25045687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/606870
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