Tracking antigen- specific CD4(+) T cells throughout the course of chronic Leishmania major infection in resistant mice

Primary Leishmania major infection typically produces cutaneous lesions that heal but that harbor persistent parasites. While the opposing roles of CD4(+) T cell-derived IFN-γ and IL-10 in promoting parasite killing and persistence have been well established, how these responses develop from naïve p...

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Main Authors: Pagán, Antonio J., Peters, Nathan C., Debrabant, Alain, Ribeiro-Gomes, Flavia, Pepper, Marion, Karp, Christopher L., Jenkins, Marc K., Sacks, David L.
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4086308/
https://ncbi.nlm.nih.gov/pubmed/23109292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201242715
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