Tracking antigen- specific CD4(+) T cells throughout the course of chronic Leishmania major infection in resistant mice

Primary Leishmania major infection typically produces cutaneous lesions that heal but that harbor persistent parasites. While the opposing roles of CD4(+) T cell-derived IFN-γ and IL-10 in promoting parasite killing and persistence have been well established, how these responses develop from naïve p...

Full description

Saved in:
Bibliographic Details
Main Authors: Pagán, Antonio J., Peters, Nathan C., Debrabant, Alain, Ribeiro-Gomes, Flavia, Pepper, Marion, Karp, Christopher L., Jenkins, Marc K., Sacks, David L.
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4086308/
https://ncbi.nlm.nih.gov/pubmed/23109292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201242715
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items