Quantification of the infectious dose of Leishmania major transmitted to the skin by single sand flies

Leishmaniasis is transmitted between mammalian hosts by the bites of bloodsucking vector sand flies. The dose of parasites transmitted to the mammalian host has never been directly determined. We developed a real-time PCR-based method to determine the number of Leishmania major parasites inoculated...

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Bibliographic Details
Main Authors: Kimblin, Nicola, Peters, Nathan, Debrabant, Alain, Secundino, Nagila, Egen, Jackson, Lawyer, Phillip, Fay, Michael P., Kamhawi, Shaden, Sacks, David
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2008
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2481378/
https://ncbi.nlm.nih.gov/pubmed/18626016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0802331105
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