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Quantification of the infectious dose of Leishmania major transmitted to the skin by single sand flies

Leishmaniasis is transmitted between mammalian hosts by the bites of bloodsucking vector sand flies. The dose of parasites transmitted to the mammalian host has never been directly determined. We developed a real-time PCR-based method to determine the number of Leishmania major parasites inoculated...

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Detalhes bibliográficos
Main Authors: Kimblin, Nicola, Peters, Nathan, Debrabant, Alain, Secundino, Nagila, Egen, Jackson, Lawyer, Phillip, Fay, Michael P., Kamhawi, Shaden, Sacks, David
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2481378/
https://ncbi.nlm.nih.gov/pubmed/18626016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0802331105
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