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Quantification of the infectious dose of Leishmania major transmitted to the skin by single sand flies

Leishmaniasis is transmitted between mammalian hosts by the bites of bloodsucking vector sand flies. The dose of parasites transmitted to the mammalian host has never been directly determined. We developed a real-time PCR-based method to determine the number of Leishmania major parasites inoculated...

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Autors principals: Kimblin, Nicola, Peters, Nathan, Debrabant, Alain, Secundino, Nagila, Egen, Jackson, Lawyer, Phillip, Fay, Michael P., Kamhawi, Shaden, Sacks, David
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2481378/
https://ncbi.nlm.nih.gov/pubmed/18626016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0802331105
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