Transplantation of ex vivo expanded cord blood cells using the copper chelator tetraethylenepentamine: a phase I/II clinical trial

The copper chelator tetraethylenepentamine (TEPA; StemEx) was shown to attenuate the differentiation of ex vivo cultured hematopoietic cells resulting in preferential expansion of early progenitors. A phase I/II trial was performed to test the feasibility and safety of transplantation of CD133+ cord...

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Main Authors: de Lima, M, McMannis, J, Gee, A, Komanduri, K, Couriel, D, Andersson, BS, Hosing, C, Khouri, I, Jones, R, Champlin, R, Karandish, S, Sadeghi, T, Peled, T, Grynspan, F, Daniely, Y, Nagler, A, Shpall, EJ
Format: Artigo
Language:Inglês
Published: 2008
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4086223/
https://ncbi.nlm.nih.gov/pubmed/18209724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bmt.1705979
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