Intravenous Busulfan Plus Melphalan Is a Highly Effective, Well-Tolerated Preparative Regimen for Autologous Stem Cell Transplantation in Patients with Advanced Lymphoid Malignancies

We investigated the administration of intravenous (i.v.) busulfan (Bu) combined with melphalan (Mel) in patients with advanced lymphoid malignancies undergoing autologous SCT. Bu 130 mg/m(2) was infused daily for 4 days, either as a fixed dose per BSA, or to target an average daily AUC of 5,000 uMol...

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Detalhes bibliográficos
Main Authors: Kebriaei, P, Madden, T, Kazerooni, R, Wang, X, Thall, P, Ledesma, C, Nieto, Y, shpall, EJ, Hosing, C, Qazilbash, M, Popat, U, Khouri, I, Champlin, RE, Jones, RB, Andersson, BS
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4031688/
https://ncbi.nlm.nih.gov/pubmed/20674757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbmt.2010.07.016
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