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Ligand-induced structural changes in the cyclic nucleotide-modulated potassium channel MloK1
Cyclic nucleotide-modulated ion channels are important for signal transduction and pacemaking in eukaryotes. The molecular determinants of ligand gating in these channels are still unknown, mainly because of a lack of direct structural information. Here we report ligand-induced conformational change...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Pub. Group
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4086158/ https://ncbi.nlm.nih.gov/pubmed/24469021 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms4106 |
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