Ligand-induced structural changes in the cyclic nucleotide-modulated potassium channel MloK1

Cyclic nucleotide-modulated ion channels are important for signal transduction and pacemaking in eukaryotes. The molecular determinants of ligand gating in these channels are still unknown, mainly because of a lack of direct structural information. Here we report ligand-induced conformational change...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Kowal, Julia, Chami, Mohamed, Baumgartner, Paul, Arheit, Marcel, Chiu, Po-Lin, Rangl, Martina, Scheuring, Simon, Schröder, Gunnar F., Nimigean, Crina M., Stahlberg, Henning
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Pub. Group 2014
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4086158/
https://ncbi.nlm.nih.gov/pubmed/24469021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms4106
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