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A web-based interactive framework to assist in the prioritization of disease candidate genes in whole-exome sequencing studies

Whole-exome sequencing has become a fundamental tool for the discovery of disease-related genes of familial diseases and the identification of somatic driver variants in cancer. However, finding the causal mutation among the enormous background of individual variability in a small number of samples...

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Detalhes bibliográficos
Main Authors: Alemán, Alejandro, Garcia-Garcia, Francisco, Salavert, Francisco, Medina, Ignacio, Dopazo, Joaquín
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4086071/
https://ncbi.nlm.nih.gov/pubmed/24803668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku407
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