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Efficacy and mechanism of poloxamine-assisted polyplex transfection

BACKGROUND: Amphiphilic block copolymers acting as biological response modifiers provide an attractive approach to improving the transfection efficiency of polycationic polymer/DNA complexes (polyplexes) by altering cellular processes crucial to efficient transgene expression. METHODS: The objective...

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Bibliographic Details
Main Authors: Zhang, Jeremy, Bae, Sooneon, Lee, Jeoung Soo, Webb, Ken
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4085676/
https://ncbi.nlm.nih.gov/pubmed/23813893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jgm.2719
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