Targeted Resequencing and Systematic In Vivo Functional Testing Identifies Rare Variants in MEIS1 as Significant Contributors to Restless Legs Syndrome

Restless legs syndrome (RLS) is a common neurologic condition characterized by nocturnal dysesthesias and an urge to move, affecting the legs. RLS is a complex trait, for which genome-wide association studies (GWASs) have identified common susceptibility alleles of modest (OR 1.2–1.7) risk at six ge...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Schulte, Eva C., Kousi, Maria, Tan, Perciliz L., Tilch, Erik, Knauf, Franziska, Lichtner, Peter, Trenkwalder, Claudia, Högl, Birgit, Frauscher, Birgit, Berger, Klaus, Fietze, Ingo, Hornyak, Magdolna, Oertel, Wolfgang H., Bachmann, Cornelius G., Zimprich, Alexander, Peters, Annette, Gieger, Christian, Meitinger, Thomas, Müller-Myhsok, Bertram, Katsanis, Nicholas, Winkelmann, Juliane
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2014
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4085638/
https://ncbi.nlm.nih.gov/pubmed/24995868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2014.06.005
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados