Different design of enzyme-triggered CO-releasing molecules (ET-CORMs) reveals quantitative differences in biological activities in terms of toxicity and inflammation

Acyloxydiene–Fe(CO)(3) complexes can act as enzyme-triggered CO-releasing molecules (ET-CORMs). Their biological activity strongly depends on the mother compound from which they are derived, i.e. cyclohexenone or cyclohexanedione, and on the position of the ester functionality they harbour. The pres...

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Main Authors: Stamellou, E., Storz, D., Botov, S., Ntasis, E., Wedel, J., Sollazzo, S., Krämer, B.K., van Son, W., Seelen, M., Schmalz, H.G., Schmidt, A., Hafner, M., Yard, B.A.
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2014
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4085349/
https://ncbi.nlm.nih.gov/pubmed/25009775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2014.06.002
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