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New approaches to the management of schizophrenia: focus on aberrant hippocampal drive of dopamine pathways

Schizophrenia is a disease affecting up to 1% of the population. Current therapies are based on the efficacy of chlorpromazine, discovered over 50 years ago. These drugs block dopamine D2-like receptors and are effective at primarily treating positive symptoms in a subset of patients. Unfortunately,...

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Autori principali: Perez, Stephanie M, Lodge, Daniel J
Natura: Artigo
Lingua:Inglês
Pubblicazione: Dove Medical Press 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4085299/
https://ncbi.nlm.nih.gov/pubmed/25061280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S42708
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