CHRONIC CYCLIC BLADDER OVER-DISTENSION UPREGULATES HYPOXIA-DEPENDENT PATHWAYS

PURPOSE: Bladder over-distension secondary to anatomic or functional obstruction can eventually lead to pathologic changes, including decreased elasticity and contractile dysfunction. We hypothesize that chronic bladder distension in a murine model will activate hypoxia-dependent signaling pathways...

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Main Authors: Stephany, Heidi A., Strand, Douglas W., Ching, Christina B., Tanaka, Stacy T., Milne, Ginger L., Cajaiba, Mariana M., Thomas, John C., Pope, John C., Adams, Mark C., Brock, John W., Hayward, Simon W., Matusik, Robert J., Clayton, Douglass B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4085185/
https://ncbi.nlm.nih.gov/pubmed/23429070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.juro.2013.02.026
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