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CHRONIC CYCLIC BLADDER OVER-DISTENSION UPREGULATES HYPOXIA-DEPENDENT PATHWAYS

PURPOSE: Bladder over-distension secondary to anatomic or functional obstruction can eventually lead to pathologic changes, including decreased elasticity and contractile dysfunction. We hypothesize that chronic bladder distension in a murine model will activate hypoxia-dependent signaling pathways...

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Autors principals: Stephany, Heidi A., Strand, Douglas W., Ching, Christina B., Tanaka, Stacy T., Milne, Ginger L., Cajaiba, Mariana M., Thomas, John C., Pope, John C., Adams, Mark C., Brock, John W., Hayward, Simon W., Matusik, Robert J., Clayton, Douglass B.
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4085185/
https://ncbi.nlm.nih.gov/pubmed/23429070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.juro.2013.02.026
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