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Rapid downregulation of rat renal Na/P(i) cotransporter in response to parathyroid hormone involves microtubule rearrangement

Renal proximal tubule cells express in their apical brush border membrane (BBM) a Na/P(i) cotransporter type IIa that is rapidly downregulated in response to parathyroid hormone (PTH). We used the rat renal Na/P(i) cotransporter type IIa (NaPi-2) as an in vivo model to assess early cellular events i...

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Udgivet i:J Clin Invest
Principais autores: Lötscher, Marius, Scarpetta, Yvonne, Levi, Moshe, Halaihel, Nabil, Wang, Huamin, Zajicek, Hubert K., Biber, Jürg, Murer, Heini, Kaissling, Brigitte
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 1999
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Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC408517/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10449440/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI3208
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