Rapid downregulation of rat renal Na/P(i) cotransporter in response to parathyroid hormone involves microtubule rearrangement

Renal proximal tubule cells express in their apical brush border membrane (BBM) a Na/P(i) cotransporter type IIa that is rapidly downregulated in response to parathyroid hormone (PTH). We used the rat renal Na/P(i) cotransporter type IIa (NaPi-2) as an in vivo model to assess early cellular events i...

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Main Authors: Lötscher, Marius, Scarpetta, Yvonne, Levi, Moshe, Halaihel, Nabil, Wang, Huamin, Zajicek, Hubert K., Biber, Jürg, Murer, Heini, Kaissling, Brigitte
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 1999
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC408517/
https://ncbi.nlm.nih.gov/pubmed/10449440
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