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A High-Throughput Screen for Antibiotic Drug Discovery
We describe an ultra-high-throughput screening platform enabling discovery and/or engineering of natural product antibiotics. The methodology involves creation of hydrogel-in-oil emulsions in which recombinant microorganisms are co-emulsified with bacterial pathogens; antibiotic activity is assayed...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4085149/ https://ncbi.nlm.nih.gov/pubmed/23955804 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bit.25019 |
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