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The C2 domains of granuphilin are high-affinity sensors for plasma membrane lipids
Membrane-targeting proteins are crucial components of many cell signaling pathways, including the secretion of insulin. Granuphilin, also known as synaptotagmin-like protein 4, functions in tethering secretory vesicles to the plasma membrane prior to exocytosis. Granuphilin docks to insulin secretor...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4085138/ https://ncbi.nlm.nih.gov/pubmed/24184645 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chemphyslip.2013.10.009 |
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