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Compound activity prediction using models of binding pockets or ligand properties in 3D

Transient interactions of endogenous and exogenous small molecules with flexible binding sites in proteins or macromolecular assemblies play a critical role in all biological processes. Current advances in high-resolution protein structure determination, database development, and docking methodology...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kufareva, Irina, Chen, Yu-Chen, Ilatovskiy, Andrey V., Abagyan, Ruben
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4085113/
https://ncbi.nlm.nih.gov/pubmed/23116466
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