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Druggable Exosites of the Human Kino-Pocketome
Small molecules binding at any of the multiple regulatory sites on the molecular surface of a protein kinase may stabilize or disrupt the corresponding interaction, leading to consequent modulation of the kinase cellular activity. As such, each of these sites represents a potential drug target. Even...
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| Pubblicato in: | J Comput Aided Mol Des |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7082431/ https://ncbi.nlm.nih.gov/pubmed/31925639 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10822-019-00276-y |
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