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miR-34a functions as a tumor suppressor modulating EGFR in glioblastoma multiforme
Chromosome 1p36.23 is frequently deleted in glioblastoma multiforme (GBM). miR-34a localizes in this region. Our experiments found that miR-34a was often deleted and epidermal growth factor receptor (EGFR) was frequently amplified in genomic DNA of 55 GBMs using single-nucleotide polymorphism DNA mi...
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| 主要な著者: | , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4085050/ https://ncbi.nlm.nih.gov/pubmed/22580610 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2012.132 |
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