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miR-34a functions as a tumor suppressor modulating EGFR in glioblastoma multiforme
Chromosome 1p36.23 is frequently deleted in glioblastoma multiforme (GBM). miR-34a localizes in this region. Our experiments found that miR-34a was often deleted and epidermal growth factor receptor (EGFR) was frequently amplified in genomic DNA of 55 GBMs using single-nucleotide polymorphism DNA mi...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4085050/ https://ncbi.nlm.nih.gov/pubmed/22580610 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2012.132 |
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