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miR-34a functions as a tumor suppressor modulating EGFR in glioblastoma multiforme

Chromosome 1p36.23 is frequently deleted in glioblastoma multiforme (GBM). miR-34a localizes in this region. Our experiments found that miR-34a was often deleted and epidermal growth factor receptor (EGFR) was frequently amplified in genomic DNA of 55 GBMs using single-nucleotide polymorphism DNA mi...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Yin, D, Ogawa, S, Kawamata, N, Leiter, A, Ham, M, Li, D, Doan, NB, Said, JW, Black, KL, Koeffler, H Phillip
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2012
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4085050/
https://ncbi.nlm.nih.gov/pubmed/22580610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2012.132
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