Thymoquinone Induces Cell Death in Human Squamous Carcinoma Cells via Caspase Activation-Dependent Apoptosis and LC3-II Activation-Dependent Autophagy

BACKGROUND: Thymoquinone (TQ), an active component of Nigella sativa or black cumin, elicits cytotoxic effects on various cancer cell lines. However, the anti-cancer effects of TQ on head and neck squamous cell carcinoma (HNSCC) remain unclear. METHODOLOGY/PRINCIPAL FINDINGS: In this study, TQ elici...

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Hlavní autoři: Chu, Shu-Chen, Hsieh, Yih-Shou, Yu, Cheng-Chia, Lai, Yi-Yeh, Chen, Pei-Ni
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2014
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4085014/
https://ncbi.nlm.nih.gov/pubmed/25000169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0101579
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