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Thymoquinone Inhibits Autophagy and Induces Cathepsin-Mediated, Caspase-Independent Cell Death in Glioblastoma Cells

Glioblastoma is the most aggressive and common type of malignant brain tumor in humans, with a median survival of 15 months. There is a great need for more therapies for the treatment of glioblastoma. Naturally occurring phytochemicals have received much scientific attention because many exhibit pot...

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Autori principali: Racoma, Ira O., Meisen, Walter Hans, Wang, Qi-En, Kaur, Balveen, Wani, Altaf A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3767730/
https://ncbi.nlm.nih.gov/pubmed/24039814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0072882
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