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Polymer-peptide delivery platforms: effect of oligopeptide orientation on polymer-based DNA delivery
The success of non-viral transfection using polymers hinges on efficient nuclear uptake of nucleic acid cargo and overcoming intra- and extracellular barriers. By incorporating PKKKRKV heptapeptide pendent groups as nuclear localization signals (NLS) on a polymer backbone, we demonstrate protein exp...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4084789/ https://ncbi.nlm.nih.gov/pubmed/24606402 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bm401878p |
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