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Solution NMR and Computational Methods for Understanding Protein Allostery

Allosterism is an essential biological regulatory mechanism. In enzymes, allosteric regulation results in an activation or inhibition of catalytic turnover. The mechanisms by which this is accomplished are unclear and vary significantly depending on the enzyme. It is commonly the case that a metabol...

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Detalles Bibliográficos
Main Authors: Manley, Gregory, Rivalta, Ivan, Loria, J. Patrick
Formato: Artigo
Idioma:Inglês
Publicado: 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4084788/
https://ncbi.nlm.nih.gov/pubmed/23445323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp312576v
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