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Solution NMR and Computational Methods for Understanding Protein Allostery

Allosterism is an essential biological regulatory mechanism. In enzymes, allosteric regulation results in an activation or inhibition of catalytic turnover. The mechanisms by which this is accomplished are unclear and vary significantly depending on the enzyme. It is commonly the case that a metabol...

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Détails bibliographiques
Auteurs principaux: Manley, Gregory, Rivalta, Ivan, Loria, J. Patrick
Format: Artigo
Langue:Inglês
Publié: 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4084788/
https://ncbi.nlm.nih.gov/pubmed/23445323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp312576v
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