Rapid generation of broad T-cell immunity in humans after a single injection of mature dendritic cells

Dendritic cells (DCs) are potent antigen-presenting cells that initiate protective T-cell immunity in mice. To study the immunogenicity of DCs in humans, we injected 9 healthy subjects subcutaneously with a control injection of autologous monocyte-derived, mature DCs, followed 4–6 weeks later by DCs...

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Hauptverfasser: Dhodapkar, Madhav V., Steinman, Ralph M., Sapp, Mark, Desai, Hema, Fossella, Coraleen, Krasovsky, Joseph, Donahoe, Sean M., Dunbar, P. Rod, Cerundolo, Vincenzo, Nixon, Douglas F., Bhardwaj, Nina
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 1999
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC408478/
https://ncbi.nlm.nih.gov/pubmed/10411546
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